SPOLIER ALERT: They killed off Brian. But you already knew that.
P.S. It is possible Seth MacFarlane has felt Family Guy has gone on long enough. Most shows arc within 5-7 seasons, which can feel like an eternity (The Office, anyone?). Family Guy is well into its teenage years.
Perhaps MacFarlane is tanking Family Guy on purpose, in which case, all bets are off. He’ll kill of Peter next week. And Stewie the week after that. And by the end, only Mayor Adam West will remain.